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Science
Publications and Presentations
Check out our publications and poster presentations.
June 2016
Phase 1 study of CB-839, a small molecule inhibitor of glutaminase, alone and in combination with everolimus in patients with renal cell cancer Phase 1 study of CB-839, a small molecule inhibitor of glutaminase in combination with paclitaxel in patients with triple negative breast cancerAmerican Society of Clinical Oncology – June 2016
April 2016
Immuno-Oncology Agent CB-1158 is a Potent and Selective Arginase Inhibitor and Causes an Immune-Mediated Anti-Tumor ResponseAmerican Association of Cancer Research – April 2016
April 2016
Glutaminase Inhibition With CB-839 Enhances Anti-Tumor Activity of PD-1 and PD-L1 Antibodies by Overcoming a Metabolic Checkpoint Blocking T Cell ActivationAmerican Association of Cancer Research – April 2016
March 2016
Arginase Inhibitor CB-1158 is a Novel Immuno-Oncology Agent that Targets Tumor-Infiltrating Suppressive Myeloid CellsKeystone Symposia on Cancer Immunotherapy
December 2015
Metabolomic, Proteomic and Genomic Profiling Identifies Biomarkers of Sensitivity to Glutaminase Phase I Study of CB-839, a First-in-class, Orally Administered Small Molecule Inhibitor of Glutaminase in Patients With Relapsed/ Refractory Leukemia Phase I Study of CB-839, a First-in-class, Glutaminase Inhibitor in Patients With Multiple Myeloma and LymphomaAmerican Society of Hematology
Our Pipeline
We are focused on solid tumors for
which new treatments are urgently needed.